Contraindications:
Buy Cipro 500mg is not recommended for the intake to the patients with hypersensitivity to the ciprofloxacin or any other drug component, as well as for the other drugs of the fluoroquinolones group. Buy Cipro treatment cannot be combined with the ciprofloxacin or tizanidine intake due to the clinically significant side effects (such as arterial hypotension and drowsiness), caused by the increase of tizanidine concentration in the blood. Buy Cipro Online shouldn't also be prescribed to the pregnant women and to the nursing mothers. As the other antibiotics Buy Cipro is not recommended for the intake without doctor's prescription.
Pharmacokinetics:
After the peroral administration Cipro is very well absorbed - mostly in the duodenum and in the upper part of the small intestine. The drug Cmax in the blood plasma is reached in 60-120 minutes after the intake. The Buy Cipro bioactivity is 70-80%. The drug is excreted mostly through the kidneys (about 45% are excreted unchanged, and 11% are excreted in the form of metabolites). The rest of the drug dose is excreted through the bowels (about 20% are excreted unchanged, and 5-6% are excreted in the form of the metabolites).
Dosage and method of application:
The daily dose of Cipro recommended to adult patients is 500mg for 1 or 2 administrations. If necessary the dose of 500mg twice for 24 hours can be prescribed. In case of rheumatoid arthritis the total daily dose of 250-500 mg for two intakes is recommended. For the aged patients or patients with moderate compromised liver function it is better to start the Buy Cipro treatment with the minimum recommended dose.